DC 7

PhD Position (m/f/d) Development of a bioresorbable Mg/Zn coronary stent for the treatment of coronary artery disease

Project Description

Bioabsorbable coronary stents address the need for improved long-term outcomes and reduced complications in the treatment of coronary artery disease. Unlike traditional metallic stents, bioabsorbable stents are designed to gradually dissolve over time, reducing long-term complications, such as in-stent restenosis (re-narrowing of the artery) and the formation of blood clots. This project will develop a bioabsorbable coronary stent device with from either preferred Mg & Zn alloy, targeting a thin strut design that achieves high radial strength, low recoil.

The objectives of this project are:

(i) Establish Design I/O matrix based on user needs and explore design concepts for coronary artery stent from either preferred Mg & Zn alloy through finite element simulation using Abaqus simulation software.

(ii) Production of early design prototypes and conduct in vitro bench testing of functional mechanical performance and corrosion behaviour.

(iii) Conduct further computational design optimisation and verification of late-stage prototype devices from Mg or Zn alloys, as per ISO 25539- 2 (e.g. radial force, bending behaviour, crush resistance, crimpability).

This project would suit a candidate with an academic qualification in Mechanical, Biomedical or Materials Engineering (or related disciplines), and previous experience in experimental characterisation or computational modelling of medical devices desirable.

Recruiting partner

University of Galway, Galway, Ireland

PhD enrollment

University of Galway, Galway, Ireland

Secondment host

B. Braun, Melsungen, Germany

Associated host

Uniklinik Aachen, MK1 Klinik für Kardiologie, Angiologie und Internistische Intensivmedizin, Aachen, Germany

Lead Supervisors

Prof. Ted Vaughan (Galway)
Mr Felix Fulda (BBraun)
Prof. Dr. med. Felix Vogt (Uniklinik Aachen)

For further details or queries about this project, please contact
BIOMEND@universityofgalway.ie

Interested?

Apply now.